Toxicidad pulmonar inducida por sales de oro / Gold salt-induced lung disease

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[Bladder leiomyosarcoma in a young man with a transplant. Report of a case]. / Leiomiosarcoma vesical en joven trasplantado. Aportación de un caso.

Contribution of one case of a 24-year-old patient, with a renal graft, who was diagnosed with vesical leyomiosarcoma. Radical cystectomy with ureterosygmoidostomy was performed. The rarity of vesical sarcoma, both in normal population or among those undergoing transplantation, as well as the greater tendency of transplanted patients to suffer malignant neoplasia, are emphasised.

Transplant aspirative cytology: analysis of morphological and immunocytochemical parameters in renal allograft dysfunction.

We have analyzed 245 transplant aspirative cytologies (TACs) from 96 renal allograft patients. TACs were divided in two chronological groups: Early (TACs performed during the first 3-mo posttransplantation) and late (TACs performed after the third month post-transplantation), in order to assess the effect of allograft tolerance on TAC features. Both morphological and immunocytochemical aspects were evaluated, including CD4, CD8, IL2-R, and HLA-DR immunolabeling. A final diagnosis for each case of allograft dysfunction was achieved by other independent diagnostic means. Four diagnostic groups were considered in the present study: acute rejection (AR), chronic rejection (CR), acute tubular necrosis (ATN), and Cyclosporin A toxicity (CsA-T). In addition, a control group (C) was established from patients with stable allograft function. We found that immunocytochemical analysis of TACs is particularly helpful in the diagnosis of late allograft dysfunction, a time period when the simple cytological study of renal infiltrate is not informative enough to help take therapeutic decisions.